Congrats to Olivia for being awarded the Michael Rinaldi Post-Doctoral Travel Award from the Medical Mycological Society of America!

We wish our research technician, Kyle Basham, the best of luck as he starts his new job as a Medical Assistant at Mount Auburn. We will miss your positivity and kindness in the lab!

Olivia presented her recent work on Coccidioides at the 69th Annual Coccidioidomycosis Study Group!

Jay and Hannah attended the 2025 GRC on the Immunology of Fungal Infections in California.

Dr. Hannah Brown Harding was awarded a travel award from the Journal of Fungi for the ISHAM meeting. Congrats!

Jay led a discussion on managing wellness on physician-scientist development at the 2024 European MD/PhD Association Conference!

After 28 years of being at MGH, Jay accepted a new position at Columbia University! He is now the Roy and Diana Vagelos Professor in the Department of Medicine, Division of Infectious Disease, Associate Dean for Academic Innovation and the Director of Physician Scientist Programs at the Vagelos Institute of Biomedical Research Education. The lab will slowly transition over the next year.

Jay gave a keynote presentation at the European MD/PhD Association Conference!

Hannah and Jay attended the Cytokines 2024 Meeting in Seoul. Hannah did a great job presenting her recent work!

Congrats to Jay on receiving the APDIM DIstinguished University Medical Educator Award!

Check out our recent pre-print on the use of single-cell RNA sequencing of human airway epithelium following infection with two fungal pathogens!

Jay participated in the Rally for Medical Research in support of basic and biomedical research budget in Washington, DC!

As part of the POSITIVES Study Team, Jay and Tammy recently published on emerging SARS-CoV-2 resistance after antiviral treatment in JAMA Network Open.

Congrats to Jay on his recent commentary in JAMA Network Open

Jay and former post-doc, Dr. Jennifer Reedy, recently were co-authors on the paper entitled “Blocking HXA3-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia”.

Congrats to Dr. Hannah Brown Harding on receiving the Pathogens 2024 Young Investigator Award!

Our paper on fungal melanin blocking pro-inflammatory responses in airway epithelium has been officially published in Nature Communications! Check out it now!

Our work was selected as the cover of the June Issue of JCI Insight in tandem with our BTK story.

Congrats to Geneva on her first author and Hannah on her corresponding author review article published in Extracellular Vesicle discussing pathogen EVs in the host immune system.

Congrats to Jay on his promotion to Professor at Harvard Medical School!

Our paper in JCI Insight is officially available! Check out our recent work exploring the role of BTK inhibition on neutrophil effector functions against Aspergillus and the restoration of these activities by TNFα.

Congrats to Hannah Brown Harding for being named a Broad Ignite Fellow!

Jay was elected as a fellow of the American Association for the Advancement of Science (AAAS)!

Congrats to the lab for a double publication acceptance day! Be on the lookout for our new review article on pathogen extracellular vesicles in host immunity and a primary article on the role of BTK inhibition on anti-Aspergillus neutrophil function.

Jay appeared on the Not Otherwise Specified podcast from the New England Journal of Medicine to discuss the benefits and risks of the new wave of trainee unionization.

Our collaborators recently published their work in Cell Reports on the phosphorylation switch in CARD9 required for innate inflammatory responses.

We recently attended the 2024 Keystone Symposium on Fungal Pathogens: Emerging Threats and Future Challenges! Jay presented some of our recent work, while Hannah, Kirstine, and Olivia presented posters of their work!

Congrats to Jay, Tammy, and their collaborators on the publication in Sci Transl Med on SARS-CoV-2 viral clearance and evolution.

Our recent paper at Nat Microbiol on the role of cGAS-STING signaling in response to Candida infection is officially available! Also, check out the selected journal cover, created by Hannah!

Our collaborators published their recent work on microfold cells in the airway epithelium in the Am J Respir Cell Mol Biol.

Congrats to Hannah and the rest of the team on the acceptance of their manuscript on the role of type I IFNs in Candida albicans infections in Nature Microbiology!

We welcome Dr. Olivia Hepworth to the lab as a post-doc. Olivia recently completed her PhD at King’s College London.

Welcome to our new post-doc, Dr. Kirstine Nolling Jensen, who recently completed her PhD at the University of Iceland!

Jay announced that he would be stepping down as the MGH Internal Medicine Residency Program Director. Congrats on a successful tenure!

Becca led a roundtable at the 2023 annual AMWA meeting, focusing on building institutional support for scientific writers and editors in academic medicine.

We wish our research technician, Chris Reardon, the best of luck as he starts a new position at Ring Therapeutics.

Jay appeared on the Behind the Microscope Podcast to discuss his philosophies on team science and physician-scientist training.

Congrats to Jay on his recent publication on the differential skin immunre responses to Candida spp in Microbiology Spectrum.

We welcomed Geneva and Patricia back to the lab as research technicians!

Jay shared some of our recent work at MycoTalks hosted by the MRC Centre for Medical Mycology. The recording can be found on their YouTube channel!

Congrats to our collaborators in the Rajagopal lab for the recent acceptance on their manuscript to Am J Respir Cell Mol Biol focused on airway microfold cells! The preprint version is currently available online.

Congrats to Jay for being named a Fellow of the European Confederation of Medical Mycology (FECMM)!

Best of luck to Jen Reedy on her new adventure at Vertex Pharmaceuticals! We are excited for your next adventure.

We recently celebrated Ari Crossen’s contribution to the lab over the past 3.5 years. Ari will enter the PhD program in microbiology at the University of Colorado.

Hannah presented her recent work on the role of extracellular vesicles in triggering type I IFN responses to Candida infection at the 2023 Candida and Candidiasis Meeting in Montreal.

Congrats to Jay on his recent review on coccidioidomycosis in J Fungi.

Congrats to our lab alumna Mary Feliu for graduating with her MD from Ohio State School of Medicine!

Jay served as SUNY Upstate’s 2023 AOA Society Visiting Professor.

Check out our pre-print on the effects of fungal melanin on airway epithelium. Revisions pending for Nat Comm.

Congrats to Jay for being elected as a fellow of the American Academy of Microbiology!

Good luck to our postdoc, Diego, on his upcoming position with Orbital Therapeutics. We wish you luck in all your future endeavors.

Many of the lab traveled to Texas to present their work at the Gordon Research Conference and accompanying Seminar on the Immunology of Fungal Infections. Congrats to Jay (the conference Chair) and the rest of the planning committee for a successful meeting.

Congrats to Jay and Becca on their recent grant for the NIA R38 Diseases of Aging Pathway StARR, focusing on providing the opportunity to conduct a year of research during residency in the areas of Alzheimer’s disease and related dementia (ADRD), frailty, and multimorbidity in aging

We are proud to announce that Dr. Hannah Brown was awarded the 2023 MGH ECOR Fund for Medical Discovery Fundamental Research Fellowship!

Congrats to Jen on her recent publication on Dectin-2 as a receptor for Aspergillus galactomannan in mBio.

Congrats to Ari and Becca on the publication of their shared first-author review article focused on human airway epithelium in response to fungi published in J Fungi

It’s official! We are now BSL3 approved to work with Coccidioides! Congrats to Ari and Kyle for finishing their training.

Our scientific writer, Becca, kicked off the second annual grant writing course for the MGH Center of Faculty Development.

Congrats to Jay and Tammy for their recent publication on vaccine breakthrough infections and neutralizing antibody responses in JCI Insights.

Members of the lab attended the New England Conference 2022!

Congrats to the team (including Jay and Tammy) for their publication on the duration of shedding culturable SARS-CoV-2 Omicron infection in NEJM.

Jay and Tammy were part of the study team for a recent publication in Clin Infect Dis focusing on virologic rebound following nirmatrelvir-ritonavir treatment for COVID.

Welcome to the lab Kyle Basham! Kyle is a recent graduate from California Baptist University and joins the lab as a research technician.

Welcome to the lab Chris Reardon! Chris is a recent graduate from U Mass Amherst and joins the lab as a research technician.

The lab attended a rally in support for women’s reproductive rights sponsored by MGH.

The celebrated the Vyas-Mansour research technicians and thank them for all the hard work they put into their research!

The lab was awarded an R21 application to investigate the initial response of airway epithelial cells to Coccidioides.

Congrats to Jay on being named the 2022 Papadopoulos Fellow from Baylor University!

Jen posted a preprint to bioRxiv on her project examining the role of Dectin-2 in fungal infections. Peer review pending.

Hannah and Jay are the winners of the Vyas-Mansour lab’s March Madness brackets!

Tammy and Jay published their work on SARS-CoV-2 viral shedding and culture positivity in JCI Insights.

Congrats on winning the 2021 MGH outstanding program director award Jay!

Welcome to the lab Geneva Kwaku! Geneva is an undergraduate student at Dartmouth and will be working with Hannah on the interferon project.

Hannah presented her recent work at the 25th anniversary of the Molecular Mycology (MoMy) Advanced Research Training Course at Woods Hole.

Congrats to Becca on launching her Grant Writing 101 course with the MGH Center for Faculty Development!

Becca published a review on harnessing multiomics studies in infectious disease medicine in Open Forum Infectious Diseases.

Happy post-doc appreciation week to our post-docs: Hannah, Diego, and Jen!

Welcome to the lab Patricia Simaku! Patricia, an undergraduate student at Boston University, will be working with Diego.

Tammy and Jay published on asymptomatic SARS-CoV-2 among early vaccine recipients in Clinical Infectious Diseases.